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New Gene Discovery Promises Breakthrough in Heart Therapy

2/20/2025

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Summary

Story summary

A groundbreaking discovery by researchers at Amsterdam UMC and Johns Hopkins University has unveiled the SCN10a-short (S10s) gene, potentially paving the way for innovative gene therapy targeting malignant cardiac arrhythmia. This promising therapy aims to boost heart function by enhancing sodium currents in heart cells. The spin-off company, Pacing Cure, is set to advance testing for human trials.

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Story summary

A groundbreaking discovery by researchers at Amsterdam UMC and Johns Hopkins University has unveiled the SCN10a-short (S10s) gene, potentially paving the way for innovative gene therapy targeting malignant cardiac arrhythmia. This promising therapy aims to boost heart function by enhancing sodium currents in heart cells. The spin-off company, Pacing Cure, is set to advance testing for human trials.