Back to today’s briefing

Story perspectives

London Doctors Restore Vision in Four Blind Children

2/23/2025

50 7

Summary

Story summary

In a groundbreaking achievement, London doctors have restored vision in four children suffering from AIPL1-related Leber congenital amaurosis through innovative gene therapy. By injecting a functional AIPL1 gene beneath the retina, these young patients experienced remarkable visual gains over five years, even as their untreated eyes faced ongoing degeneration. However, the quest for long-term safety and efficacy data continues.

1 of 1

Story summary

In a groundbreaking achievement, London doctors have restored vision in four children suffering from AIPL1-related Leber congenital amaurosis through innovative gene therapy. By injecting a functional AIPL1 gene beneath the retina, these young patients experienced remarkable visual gains over five years, even as their untreated eyes faced ongoing degeneration. However, the quest for long-term safety and efficacy data continues.