Back to today’s briefing

Story perspectives

Study Links Brain Changes to Early Substance Use

3/5/2025

50 5

Summary

Story summary

A groundbreaking study in JAMA Network Open reveals that variations in brain structure during late childhood may signal the onset of substance use before age 15. Children who experimented with substances displayed larger brain volumes and thinner prefrontal cortices. Recognizing these early neural indicators is vital for developing effective prevention strategies against addiction and its consequences.

1 of 1

Story summary

A groundbreaking study in JAMA Network Open reveals that variations in brain structure during late childhood may signal the onset of substance use before age 15. Children who experimented with substances displayed larger brain volumes and thinner prefrontal cortices. Recognizing these early neural indicators is vital for developing effective prevention strategies against addiction and its consequences.