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Study Reveals X Chromosome Genes Boost Aging Women's Cognition

3/23/2025

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Summary

Story summary

Dormant genes on the X chromosome may awaken with age, boosting cognitive resilience in aging females more than in males, according to a new study. Researchers identified 22 reactivated genes in lab mice, notably PLP1, which aids myelin production. This discovery hints at intriguing differences in brain aging between the sexes, calling for deeper exploration in humans.

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Story summary

Dormant genes on the X chromosome may awaken with age, boosting cognitive resilience in aging females more than in males, according to a new study. Researchers identified 22 reactivated genes in lab mice, notably PLP1, which aids myelin production. This discovery hints at intriguing differences in brain aging between the sexes, calling for deeper exploration in humans.