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Breakthrough Discovery in Parkinson's: New Genes Identified

4/14/2025

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Summary

Story summary

Northwestern Medicine researchers have made a groundbreaking discovery in the fight against Parkinson's disease, identifying new genes using CRISPR technology. They found that a protein group called Commander plays a vital role in lysosomal function. Variants that impair these genes heighten the risk of Parkinson's, opening the door to potential new treatments targeting Commander proteins for this and other neurodegenerative diseases.

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Story summary

Northwestern Medicine researchers have made a groundbreaking discovery in the fight against Parkinson's disease, identifying new genes using CRISPR technology. They found that a protein group called Commander plays a vital role in lysosomal function. Variants that impair these genes heighten the risk of Parkinson's, opening the door to potential new treatments targeting Commander proteins for this and other neurodegenerative diseases.