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Long PPI Use Linked to 33% Higher Dementia Risk

4/28/2025

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Summary

Story summary

Long-term use of proton pump inhibitors (PPIs) for more than 4.4 years could raise the risk of dementia by 33%, according to a study in Neurology involving over 5,700 participants aged 45 and older. While the findings reveal a concerning link, they stop short of proving cause and effect, highlighting the need for deeper exploration.

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Story summary

Long-term use of proton pump inhibitors (PPIs) for more than 4.4 years could raise the risk of dementia by 33%, according to a study in Neurology involving over 5,700 participants aged 45 and older. While the findings reveal a concerning link, they stop short of proving cause and effect, highlighting the need for deeper exploration.