Back to today’s briefing

Story perspectives

Columbia Scientists Reveal 3D Structure of Sweet Receptor

5/10/2025

46 8

Summary

Story summary

Columbia University scientists have unveiled the intricate 3D structure of the human sweet taste receptor, TAS1R2, through cryo-electron microscopy. This groundbreaking discovery sheds light on how sweeteners attach to the receptor, paving the way for innovative sugar substitutes that could help curb sugar cravings and tackle obesity and diabetes.

1 of 1

Story summary

Columbia University scientists have unveiled the intricate 3D structure of the human sweet taste receptor, TAS1R2, through cryo-electron microscopy. This groundbreaking discovery sheds light on how sweeteners attach to the receptor, paving the way for innovative sugar substitutes that could help curb sugar cravings and tackle obesity and diabetes.