Back to today’s briefing

Story perspectives

Ohio Siblings' Hopeful Breakthrough in Rare Disorder Treatment

5/11/2025

49 11

Summary

Story summary

Three siblings from Ohio, Ava, Olivia, and Landon Langenhop, are battling LAD-1, a rare autoimmune disorder. After struggling to find bone marrow donors, they joined a groundbreaking clinical trial at UCLA. The promising therapy generated healthy immune cells in all nine participants, now awaiting FDA approval, offering hope for countless others facing similar challenges.

1 of 1

Story summary

Three siblings from Ohio, Ava, Olivia, and Landon Langenhop, are battling LAD-1, a rare autoimmune disorder. After struggling to find bone marrow donors, they joined a groundbreaking clinical trial at UCLA. The promising therapy generated healthy immune cells in all nine participants, now awaiting FDA approval, offering hope for countless others facing similar challenges.