Back to today’s briefing

Story perspectives

Breakthrough Drug Boosts Memory in Alzheimer's Models

5/22/2025

49 8

Summary

Story summary

UCLA researchers have made a groundbreaking discovery with DDL-357, a drug that boosts memory in Alzheimer’s mouse models by elevating protective protein clusterin (CLU) levels. This innovative treatment not only reduces harmful phospho-tau but also enhances cognitive function, offering hope for tackling other neurodegenerative diseases like Parkinson’s and ALS, despite being in early testing.

1 of 1

Story summary

UCLA researchers have made a groundbreaking discovery with DDL-357, a drug that boosts memory in Alzheimer’s mouse models by elevating protective protein clusterin (CLU) levels. This innovative treatment not only reduces harmful phospho-tau but also enhances cognitive function, offering hope for tackling other neurodegenerative diseases like Parkinson’s and ALS, despite being in early testing.