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Gene Mutation Explained: Why Orange Male Cats Outnumber Females

5/24/2025

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Summary

Story summary

A groundbreaking discovery reveals a genetic mutation linked to the vibrant orange fur of domestic cats. Researchers found that the ARHGAP36 gene plays a crucial role, explaining why orange males outnumber females—males need just one mutated X chromosome, while females require two. This study, published in Current Biology, sheds new light on feline genetics.

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Story summary

A groundbreaking discovery reveals a genetic mutation linked to the vibrant orange fur of domestic cats. Researchers found that the ARHGAP36 gene plays a crucial role, explaining why orange males outnumber females—males need just one mutated X chromosome, while females require two. This study, published in Current Biology, sheds new light on feline genetics.