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Ibudilast Fails to Reduce Alcohol Use in Trial

6/3/2025

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Summary

Story summary

A UCLA clinical trial revealed that ibudilast, a drug used in Japan for asthma and post-stroke dizziness, failed to outperform a placebo in curbing alcohol consumption. While some women experienced slight benefits, those with elevated depressive symptoms struggled more. This study underscores the complex link between inflammation and alcohol use disorder, sparking further inquiry into treatment options.

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Story summary

A UCLA clinical trial revealed that ibudilast, a drug used in Japan for asthma and post-stroke dizziness, failed to outperform a placebo in curbing alcohol consumption. While some women experienced slight benefits, those with elevated depressive symptoms struggled more. This study underscores the complex link between inflammation and alcohol use disorder, sparking further inquiry into treatment options.