Back to today’s briefing

Story perspectives

USC Discovery: Protein Nup98 Revolutionizes DNA Repair Mechanism

6/6/2025

34 3

Summary

Story summary

A groundbreaking discovery by scientists at USC Dornsife reveals that the protein Nup98 plays a crucial role in DNA repair by creating protective droplets around damaged DNA in heterochromatin. This innovative mechanism minimizes genetic errors associated with cancer, paving the way for targeted therapies for conditions like acute myeloid leukemia. The collaborative effort involved 17 researchers from seven institutions.

1 of 1

Story summary

A groundbreaking discovery by scientists at USC Dornsife reveals that the protein Nup98 plays a crucial role in DNA repair by creating protective droplets around damaged DNA in heterochromatin. This innovative mechanism minimizes genetic errors associated with cancer, paving the way for targeted therapies for conditions like acute myeloid leukemia. The collaborative effort involved 17 researchers from seven institutions.