Back to today’s briefing

Story perspectives

Genetic Mutation Discovered Linking Anemia to Crohn's Disease

6/11/2025

38 3

Summary

Story summary

A groundbreaking discovery by researchers at the University of California, Riverside, reveals a genetic mutation in the PTPN2 gene that exacerbates iron deficiency and anemia in Crohn's disease patients. This mutation hampers iron absorption, causing ongoing anemia even with oral supplements. The research opens the door to targeted treatments like intravenous iron therapy for those impacted.

1 of 1

Story summary

A groundbreaking discovery by researchers at the University of California, Riverside, reveals a genetic mutation in the PTPN2 gene that exacerbates iron deficiency and anemia in Crohn's disease patients. This mutation hampers iron absorption, causing ongoing anemia even with oral supplements. The research opens the door to targeted treatments like intravenous iron therapy for those impacted.