Back to today’s briefing

Story perspectives

Study Links Brain Changes to Autism Risk in 22q11.2 Deletion

6/28/2025

48 10

Summary

Story summary

A groundbreaking study in Science Advances uncovers how brain connectivity shifts before and after puberty may heighten the risk of autism and schizophrenia in children with 22q11.2 deletion syndrome. Researchers identified a transition from hyperconnectivity to hypoconnectivity during adolescence, revealing molecular factors that could pave the way for new treatment options.

1 of 1

Story summary

A groundbreaking study in Science Advances uncovers how brain connectivity shifts before and after puberty may heighten the risk of autism and schizophrenia in children with 22q11.2 deletion syndrome. Researchers identified a transition from hyperconnectivity to hypoconnectivity during adolescence, revealing molecular factors that could pave the way for new treatment options.