Back to today’s briefing

Story perspectives

Study Reveals Parkinson's May Begin in Kidneys

6/29/2025

45 5

Summary

Story summary

A groundbreaking study from Wuhan University reveals that Parkinson's disease may start in the kidneys rather than solely in the brain. Researchers discovered abnormal clumps of ?-synuclein protein in the kidney tissues of patients. Experiments on mice demonstrated that failing kidneys could enable these proteins to infiltrate the brain, opening doors to innovative treatment approaches for Parkinson's and similar conditions.

1 of 1

Story summary

A groundbreaking study from Wuhan University reveals that Parkinson's disease may start in the kidneys rather than solely in the brain. Researchers discovered abnormal clumps of ?-synuclein protein in the kidney tissues of patients. Experiments on mice demonstrated that failing kidneys could enable these proteins to infiltrate the brain, opening doors to innovative treatment approaches for Parkinson's and similar conditions.