Back to today’s briefing

Story perspectives

Revolutionary Gene Therapy Offers Hope for Blood Disorders

6/30/2025

47 11

Summary

Story summary

A groundbreaking gene therapy method, "delete-to-recruit," has been unveiled by researchers at the Hubrecht Institute and Erasmus MC. Utilizing CRISPR-Cas9, this innovative approach reactivates dormant genes by relocating them near enhancers. It holds great promise for treating sickle cell disease and beta-thalassemia, potentially providing a safer and more accessible alternative to current treatments.

1 of 1

Story summary

A groundbreaking gene therapy method, "delete-to-recruit," has been unveiled by researchers at the Hubrecht Institute and Erasmus MC. Utilizing CRISPR-Cas9, this innovative approach reactivates dormant genes by relocating them near enhancers. It holds great promise for treating sickle cell disease and beta-thalassemia, potentially providing a safer and more accessible alternative to current treatments.