Back to today’s briefing

Story perspectives

FDA-Approved Cancer Drugs Show Promise in Reversing Alzheimer's

7/28/2025

25 3

Summary

Story summary

In a groundbreaking discovery, researchers have found that two FDA-approved cancer drugs, letrozole and irinotecan, can reverse Alzheimer’s disease and restore memory in mice. By targeting toxic proteins and halting brain degeneration, this promising breakthrough ignites hope for future Alzheimer’s treatments and paves the way for accelerated human trials, as detailed in the journal Cell.

1 of 1

Story summary

In a groundbreaking discovery, researchers have found that two FDA-approved cancer drugs, letrozole and irinotecan, can reverse Alzheimer’s disease and restore memory in mice. By targeting toxic proteins and halting brain degeneration, this promising breakthrough ignites hope for future Alzheimer’s treatments and paves the way for accelerated human trials, as detailed in the journal Cell.