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Revolutionary T7-ORACLE Boosts Protein Evolution 100,000 Times

8/9/2025

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Story summary
  • A groundbreaking synthetic biology platform, T7-ORACLE, has been unveiled by scientists at Scripps Research. This innovative system harnesses a virus-derived DNA replication method to supercharge protein evolution in E. coli, achieving mutation rates an astonishing 100,000 times greater than natural processes. T7-ORACLE could revolutionize therapeutic protein development and propel biomedical research into new frontiers.