Story perspectives
UCSD Uncovers Genetic Enhancer Linked to Brain Function
8/14/2025
42 7
1 of 1
Story summary
- UC San Diego researchers discovered HAR123, a genetic enhancer associated with brain development and cognitive flexibility.
- HAR123 affects the formation of neural progenitor cells, influencing neuron and glial cell ratios.
- Knockout studies in mice indicate HAR123's importance for cognitive flexibility and its potential connection to neurodevelopmental disorders, including autism.
- Ongoing research seeks to elucidate HAR123's role in brain function and its links to various diseases.
