Back to today’s briefing

Story perspectives

New Research Links Obesity, Cancer Growth, and Gallstones

8/23/2025

28 3

Summary

Story summary

Sister Mary Joseph’s nodules (SMJNs) are associated with advanced malignancy, mainly from ovarian and gastric cancers, in 1-3% of cases.
SOX2 influences metastatic castration-resistant prostate cancer (mCRPC), promoting tumor growth and resistance to therapy.
Research connects childhood obesity to adult gallstone disease through shared gene expression affecting cholesterol metabolism and inflammation.

1 of 1

Story summary

Sister Mary Joseph’s nodules (SMJNs) are associated with advanced malignancy, mainly from ovarian and gastric cancers, in 1-3% of cases.
SOX2 influences metastatic castration-resistant prostate cancer (mCRPC), promoting tumor growth and resistance to therapy.
Research connects childhood obesity to adult gallstone disease through shared gene expression affecting cholesterol metabolism and inflammation.