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Revolutionary E. Coli Uses Fewer Codons for Life

8/26/2025

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Story summary
  • Researchers at the Medical Research Council's Laboratory of Molecular Biology created "Syn57," a bacteria with an efficient genetic code.
  • This engineered E. coli utilizes seven fewer codons than the standard 64.
  • Advances in DNA synthesis facilitated the construction of genomes from scratch, allowing for the study of alternative genetic codes.
  • The Cambridge team demonstrated that life can operate with fewer codons, marking a significant advancement in synthetic biology.