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Kyoto Researchers Develop Non-Addictive Painkiller Like Fentanyl

8/28/2025

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Story summary
  • Researchers at Kyoto University have created a new painkiller that is as effective as fentanyl but without addiction risks.
  • After 13 years of research, phase one clinical trials were successful, with phase two trials commencing soon.
  • Professor Masatoshi Hagiwara plans larger trials in the US next year, aiming for commercial availability in two years.
  • The drug alleviates pain without side effects, enabling patients to remain conscious and avoid dependence.