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Story perspectives

New Drug Aficamten Boosts Exercise in HCM Patients

8/30/2025

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Story summary
  • A study on August 30, 2025, found that Cytokinetics' drug aficamten enhanced exercise capacity in obstructive hypertrophic cardiomyopathy (HCM) patients.
  • Aficamten demonstrated a 1.1-point improvement in peak oxygen uptake compared to the beta blocker metoprolol.
  • The FDA is currently reviewing aficamten for potential approval, which may broaden its application for HCM patients.