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Story perspectives

Leqvio Outperforms Statins: 85% Achieve Cholesterol Goals

8/31/2025

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Story summary
  • Leqvio, a cholesterol-lowering injection by Novartis, helps patients reach cholesterol goals more quickly than statins.
  • In the V-DIFFERENCE trial, 85% of Leqvio patients achieved targets, versus 31% in the placebo group.
  • Leqvio patients reported 43% less muscle pain compared to those on placebo.
  • The NHS Health Survey found elevated cholesterol levels in 53% of adults in 2022, up from 43% in 2019.
  • Trial results will be presented at the European Society of Cardiology Congress in Madrid.