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Testosterone's Role in Lung Immunity Revealed in Mice

9/1/2025

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Story summary
  • A study indicates that sex hormones, especially testosterone, affect lung-resident immunity in mice.
  • Castration led to decreased neutrophils and increased B cells, while testosterone supplementation reversed these changes.
  • The research emphasizes the importance of differentiating between circulating and tissue-resident immune cells.
  • Additional studies are needed to assess the implications for respiratory diseases.