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Long-Term PPI Use Linked to 33% Dementia Risk Increase

9/2/2025

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Summary

Story summary

A Neurology study suggests long-term proton pump inhibitor (PPI) use may raise dementia risk by 33% after 4.5 years.
The research included over 5,700 participants, averaging 75 years, monitored from 1987 to 2017.
Correlation was identified, but causation remains unconfirmed; additional research is necessary.
Patients should consult healthcare providers before changing medication.

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Story summary

A Neurology study suggests long-term proton pump inhibitor (PPI) use may raise dementia risk by 33% after 4.5 years.
The research included over 5,700 participants, averaging 75 years, monitored from 1987 to 2017.
Correlation was identified, but causation remains unconfirmed; additional research is necessary.
Patients should consult healthcare providers before changing medication.