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Long-term PPI Use Linked to 33% Dementia Risk

9/2/2025

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Story summary
  • A UK study indicates long-term proton pump inhibitor (PPI) use may raise dementia risk by 33% after 4.5 years.
  • Researchers tracked 1,490 participants, identifying 585 dementia cases over 5.5 years.
  • While causation is not established, a potential link is suggested.
  • Experts advise consulting healthcare providers before changing PPI usage.