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Study: Azelastine Nasal Spray Cuts COVID-19 Rates

9/2/2025

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Summary

Story summary

A study in JAMA Internal Medicine indicates azelastine nasal spray may lower COVID-19 infection rates.
In a trial of 450 adults, the infection rate was 2.2% for azelastine users versus 6.7% for placebo.
Researchers suggest azelastine may bind the virus or inhibit its replication in the nasal mucosa.
Experts advise caution, stating it should not replace vaccinations and further research is necessary.

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Story summary

A study in JAMA Internal Medicine indicates azelastine nasal spray may lower COVID-19 infection rates.
In a trial of 450 adults, the infection rate was 2.2% for azelastine users versus 6.7% for placebo.
Researchers suggest azelastine may bind the virus or inhibit its replication in the nasal mucosa.
Experts advise caution, stating it should not replace vaccinations and further research is necessary.