Story perspectives

Genetic Links Found Between Gut Fungi and Disease Risk

9/3/2025

28 7

Summary

Story summary

Researchers at Pennsylvania State University found genetic links between human DNA, gut fungi, and chronic disease risk, published in *PLOS Biology* on September 2, 2025.
The study indicates that human genetics, not just diet, shapes gut mycobiome composition.
A genome-wide association study identified 148 fungi-associated variants linked to nine fungal taxa, highlighting their potential role in cardiovascular disease risk.
Further research is needed to understand genetic regulation of gut fungi and their interactions with gut bacteria for personalized medicine advancements.

1 of 1

Story summary

Researchers at Pennsylvania State University found genetic links between human DNA, gut fungi, and chronic disease risk, published in *PLOS Biology* on September 2, 2025.
The study indicates that human genetics, not just diet, shapes gut mycobiome composition.
A genome-wide association study identified 148 fungi-associated variants linked to nine fungal taxa, highlighting their potential role in cardiovascular disease risk.
Further research is needed to understand genetic regulation of gut fungi and their interactions with gut bacteria for personalized medicine advancements.