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Study Reveals Methotrexate Lowers Blood Pressure, Heart Risks

9/4/2025

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Summary

Story summary

A study from Flinders University indicates methotrexate, used for rheumatoid arthritis, lowers blood pressure and may reduce heart disease risk.
The research found an average systolic blood pressure decrease of 7.4 mmHg compared to sulfasalazine.
Genetic factors could affect the drug's effectiveness, highlighting the potential for personalized treatment.
Results were published in the Annals of Medicine journal.

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Story summary

A study from Flinders University indicates methotrexate, used for rheumatoid arthritis, lowers blood pressure and may reduce heart disease risk.
The research found an average systolic blood pressure decrease of 7.4 mmHg compared to sulfasalazine.
Genetic factors could affect the drug's effectiveness, highlighting the potential for personalized treatment.
Results were published in the Annals of Medicine journal.