Story perspectives
Azelastine Nasal Spray Cuts COVID-19 Infections by Two-Thirds
9/8/2025
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Story summary
- A clinical trial in JAMA Internal Medicine suggests azelastine nasal spray may protect against COVID-19.
- Conducted by Saarland University Hospital, the trial involved 450 adults in treatment and placebo groups.
- Participants used the spray or placebo three times daily for 56 days.
- The azelastine group had a 2.2% infection rate, compared to 6.7% in the placebo group.
- Further research is necessary to assess azelastine's broader preventive applications.
