Story perspectives

Study Reveals Women Face Higher Mortality on Beta-Blockers

9/9/2025

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Summary

Story summary

A study finds women face a 45% higher mortality risk than men when taking beta-blockers after a heart attack.
The REBOOT trial, involving 8,505 patients in Spain and Italy, is the largest of its kind.
Results indicate no significant benefits of beta-blockers for patients with normal heart function post-heart attack.
Women had a 2.7% higher absolute mortality risk with beta-blockers compared to untreated patients.
These findings may reshape clinical guidelines and treatment strategies for heart attack patients.

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Story summary

A study finds women face a 45% higher mortality risk than men when taking beta-blockers after a heart attack.
The REBOOT trial, involving 8,505 patients in Spain and Italy, is the largest of its kind.
Results indicate no significant benefits of beta-blockers for patients with normal heart function post-heart attack.
Women had a 2.7% higher absolute mortality risk with beta-blockers compared to untreated patients.
These findings may reshape clinical guidelines and treatment strategies for heart attack patients.