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Study Links Yersinia pestis to Plague of Justinian

9/11/2025

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Story summary
  • Researchers from USF and FAU identified Yersinia pestis as the cause of the Plague of Justinian, the first known pandemic.
  • Genomic evidence from human remains in Jerash, Jordan, confirms the plague's presence in the Byzantine Empire (AD 550-660).
  • Genetic analysis shows nearly identical Y. pestis strains among victims, indicating a rapid outbreak.
  • The study emphasizes the historical impact of pandemics, contrasting with COVID-19's single spillover event.
  • The team plans further research in Venice, Italy, to investigate early public health measures and pathogen evolution.