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Story summary
- Trent Williams, the 49ers' left tackle, is a game-time decision due to a knee injury, with his status to be confirmed after warmups. If he can't play, Spencer Burford will start.
- Wide receiver Jauan Jennings is expected to play despite a shoulder injury from Week 1, having cleared scans.
- Starting quarterback Brock Purdy is out with shoulder and toe injuries, leading to Mac Jones starting against the Saints.
- Tight end George Kittle is on injured reserve with a hamstring injury, missing at least four games.
- The 49ers aim to sustain offensive effectiveness, focusing on their running game despite these injuries.
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