Story perspectives

Study Uncovers 40 Genes Behind Left-Handedness Variability

9/15/2025

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Summary

Story summary

Approximately 10.6% of the population is left-handed, with a familial tendency.
Research identifies over 40 genes influencing handedness.
Earlier theories proposed a single gene for handedness, now disproven.
Silvia Paracchini's liability-threshold polygenic model suggests handedness is polygenic, with left-handedness arising from accumulated genetic variants.
Variability in genetic variants among left-handers complicates research, necessitating further studies.

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Story summary

Approximately 10.6% of the population is left-handed, with a familial tendency.
Research identifies over 40 genes influencing handedness.
Earlier theories proposed a single gene for handedness, now disproven.
Silvia Paracchini's liability-threshold polygenic model suggests handedness is polygenic, with left-handedness arising from accumulated genetic variants.
Variability in genetic variants among left-handers complicates research, necessitating further studies.