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Experts Warn: Nitazenes Surge Sparks Overdose Crisis

9/19/2025

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Story summary
  • Experts warn that nitazenes, synthetic opioids 20-43 times stronger than fentanyl, pose a significant overdose risk.
  • Developed in the 1950s, nitazenes were never approved for medical use due to their high potency.
  • These drugs are increasingly found in counterfeit pills sold online, often unbeknownst to users.
  • The DEA indicates that nitazenes are sourced from China and mixed with other illicit drugs, complicating overdose treatments.
  • Tennessee reports 92 nitazene-related deaths from 2019-2023, prompting officials to emphasize the need for awareness and detection tools.