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49ers Face Cardinals Without Key Stars: Jennings, Kittle Out

9/21/2025

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Summary

Story summary

Jauan Jennings will miss the game against the Arizona Cardinals due to shoulder and ankle injuries, having missed all practices last week.
In Week 2, he had five receptions for 89 yards and a touchdown despite his injuries.
Ricky Pearsall will lead as the primary wide receiver, supported by Kendrick Bourne, Marquez Valdes-Scantling, and Skyy Moore.
The 49ers will also be without tight end George Kittle and wide receiver Brandon Aiyuk.
Mac Jones will start as quarterback, with Brock Purdy sidelined by a toe injury and Adrian Martinez as his backup.

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Story summary

Jauan Jennings will miss the game against the Arizona Cardinals due to shoulder and ankle injuries, having missed all practices last week.
In Week 2, he had five receptions for 89 yards and a touchdown despite his injuries.
Ricky Pearsall will lead as the primary wide receiver, supported by Kendrick Bourne, Marquez Valdes-Scantling, and Skyy Moore.
The 49ers will also be without tight end George Kittle and wide receiver Brandon Aiyuk.
Mac Jones will start as quarterback, with Brock Purdy sidelined by a toe injury and Adrian Martinez as his backup.