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Story perspectives

Study Reveals Optimal TMS Sites for Schizophrenia Treatment

9/23/2025

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Story summary
  • A systematic review synthesizes randomized, sham-controlled trials to identify optimal non-invasive transcranial magnetic stimulation (TMS) sites for schizophrenia.
  • Endpoints span negative, cognitive, and positive symptoms; trials with concurrent therapies or missing data excluded.
  • Effect sizes use standardized mean differences with small-sample adjustments; random-effects models address heterogeneity.
  • PRISMA-compliant; 107 studies included from 4311 articles; bias assessed with Cochrane Risk of Bias Tool 2.0.