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Study Reveals Liraglutide Weight Loss Primarily Muscle, Not Fat

9/24/2025

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Summary

Story summary

In 2024, a study finds 60% of weight lost with Liraglutide is lean muscle.
Discontinuing glucagon-like peptide-1 (GLP-1) agonists often regains about two-thirds of lost weight, primarily as fat.
Orforglipron, an oral weight loss drug, shows promise with an average 27.3 pounds lost.
It may improve cardiovascular risk factors, but the weight loss is weaker than injectables.

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Story summary

In 2024, a study finds 60% of weight lost with Liraglutide is lean muscle.
Discontinuing glucagon-like peptide-1 (GLP-1) agonists often regains about two-thirds of lost weight, primarily as fat.
Orforglipron, an oral weight loss drug, shows promise with an average 27.3 pounds lost.
It may improve cardiovascular risk factors, but the weight loss is weaker than injectables.