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Bills Host Saints
- Buffalo Bills (3-0) host the New Orleans Saints (0-3) at Highmark Stadium on Sept 28, 2025; Bills favored by 16.5.
- The Saints lost 44-13 to the Seattle Seahawks and have not won this season.
- Josh Allen: 755 passing yards, five touchdowns; Spencer Rattler: 639 yards, four touchdowns.
- The over/under is 47.5, and experts expect a Bills win.
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