Story perspectives

Breakthrough Lung-On-A-Chip Enhances Personalized Medicine Research

9/25/2025

Summary

Story summary

Roy and Singh developed a lung-on-a-chip that mimics lung function and immune responses.
Chip integrates living human cells with a functioning immune system, overcoming organ-on-a-chip challenges.
It enables study of severe influenza, asthma, cystic fibrosis, lung cancer, and tuberculosis.
Influenza immune responses resemble patients, supporting personalized medicine with patient-derived cells for therapies. The findings are published in Nature Biomedical Engineering.

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Story summary

Roy and Singh developed a lung-on-a-chip that mimics lung function and immune responses.
Chip integrates living human cells with a functioning immune system, overcoming organ-on-a-chip challenges.
It enables study of severe influenza, asthma, cystic fibrosis, lung cancer, and tuberculosis.
Influenza immune responses resemble patients, supporting personalized medicine with patient-derived cells for therapies. The findings are published in Nature Biomedical Engineering.