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Story perspectives

DMT Shows Promise in Stroke Protection Research

9/27/2025

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Story summary
  • DMT may protect against stroke damage in animal and cell models.
  • It reduces infarct size, brain swelling, and inflammation, restores blood-brain barrier function, and acts via Sigma-1 receptors to limit microglial activation and support astroglial cells.
  • Trials by teams from HUN-REN BRC and Semmelweis University in Hungary are evaluating long-term effects and recovery potential, including DMT as an adjuvant therapy.