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Study Links Prenatal DNA Changes to Autism, Schizophrenia Risks

9/29/2025

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Summary

Story summary

Prenatal DNA methylation changes in the cortex are linked to autism and schizophrenia risks.
The study tracked nearly 1,000 brains from 6 weeks post-conception to 108 years old, revealing smaller, steadier postnatal changes.
Researchers identified clusters of methylation changes tied to key cortical developmental programs; the work appears in Cell Genomics.

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Story summary

Prenatal DNA methylation changes in the cortex are linked to autism and schizophrenia risks.
The study tracked nearly 1,000 brains from 6 weeks post-conception to 108 years old, revealing smaller, steadier postnatal changes.
Researchers identified clusters of methylation changes tied to key cortical developmental programs; the work appears in Cell Genomics.