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NHS Warns: Long-Term Omeprazole Use Poses Serious Risks

9/29/2025

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Story summary
  • The NHS warns of long-term risks from omeprazole, a common UK heartburn treatment.
  • Omeprazole is among the most prescribed drugs, with 73 million NHS prescriptions in England during 2022-23.
  • The NHS advises not to use omeprazole for more than two weeks without a prescription.
  • Long-term use may cause serious side effects, including a higher risk of Clostridioides difficile infection.