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New CORE Model Predicts Liver Disease Risk with 88% Accuracy

9/30/2025

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Summary

Story summary

The CORE model from Karolinska Institutet predicts severe liver disease risk from routine blood tests, age, and sex.
In a study of over 480,000 people, CORE achieved 88% accuracy, vs FIB-4's 79%.
The tool targets primary care for early detection; an online calculator estimates 10-year risk.
Validated in Finland and the UK with consistent performance; further testing needed.

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Story summary

The CORE model from Karolinska Institutet predicts severe liver disease risk from routine blood tests, age, and sex.
In a study of over 480,000 people, CORE achieved 88% accuracy, vs FIB-4's 79%.
The tool targets primary care for early detection; an online calculator estimates 10-year risk.
Validated in Finland and the UK with consistent performance; further testing needed.