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MASLD: Global Health Crisis Linked to Cardiometabolic Risks

10/1/2025

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Summary

Story summary

Metabolic dysfunction-associated steatotic liver disease (MASLD) affects more than one in three people globally.
In MASLD patients, high blood pressure raises mortality by 40%; prediabetes/diabetes by 25%; low HDL cholesterol by 15%.
Obesity increases mortality based on BMI, and each cardiometabolic risk factor adds 15%.
NHANES analyzed 134,515 participants; future work will probe genetics, diet, and alcohol to improve care.

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Story summary

Metabolic dysfunction-associated steatotic liver disease (MASLD) affects more than one in three people globally.
In MASLD patients, high blood pressure raises mortality by 40%; prediabetes/diabetes by 25%; low HDL cholesterol by 15%.
Obesity increases mortality based on BMI, and each cardiometabolic risk factor adds 15%.
NHANES analyzed 134,515 participants; future work will probe genetics, diet, and alcohol to improve care.