Story perspectives
CAR-NK Therapy Promises Breakthroughs Against Solid Tumors
10/2/2025
30 2
1 of 1
Story summary
- CAR-NK cell therapy shows potential against solid tumors, per Katy Rezvani, MD, PhD, of MD Anderson Cancer Center.
- Her work aims to enhance NK cells to overcome microenvironment challenges.
- A CRISPR screen found edits that boost NK cell resilience in hypoxia, acidity, and immunosuppression.
- Some regulators overlap CAR T cell function; others are NK-specific, and multi-gene targeting may improve efficacy.
