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New Blood Test Predicts Liver Disease Risk with 88% Accuracy

10/2/2025

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Summary

Story summary

Researchers at Karolinska Institutet developed Cirrhosis Outcome Risk Estimator (CORE) to predict liver disease risk.
CORE uses three routine blood tests (AST, ALT, GGT), plus age and sex, to estimate 10-year liver-disease risk.
In a study of over 480,000 adults, CORE achieved 88% accuracy, vs 79% for FIB-4; findings published in The British Medical Journal on September 29, 2025.

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Story summary

Researchers at Karolinska Institutet developed Cirrhosis Outcome Risk Estimator (CORE) to predict liver disease risk.
CORE uses three routine blood tests (AST, ALT, GGT), plus age and sex, to estimate 10-year liver-disease risk.
In a study of over 480,000 adults, CORE achieved 88% accuracy, vs 79% for FIB-4; findings published in The British Medical Journal on September 29, 2025.