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New Cilia Protein Map Could Transform Ciliopathy Diagnosis

10/3/2025

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Story summary
  • Researchers at KTH Royal Institute of Technology and Stanford mapped the protein composition of cilia, showing their role in sensing mechanical and chemical signals.
  • They identified 715 proteins across three cell types and found 91 unlinked proteins, with Science for Life Laboratory and the Chan Zuckerberg Imaging Institute as collaborators.
  • A CREB3 gene variant linked to ciliopathies could aid diagnosis.