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Story perspectives

New Factors Revealed for Colorectal Cancer Survival Rates

10/3/2025

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Story summary
  • Independent prognostic factors for colorectal cancer survival identified by univariate and multivariate Cox analyses using TCGA-CRC and GEO data.
  • Risk scores classify CRC samples into high/low-risk groups.
  • Gene set enrichment analysis (GSEA) identified pathways linked to risk groups.
  • Immune infiltration correlated with risk scores and immune checkpoints.
  • Key module genes identified via co-expression network construction; DESeq2 and survivalROC supported.